Small animal CT study of tumor, blood vessel, organ and bone

Application of small animal CT in bone, blood vessel, organ and tumor research

Latheta LCT-200 is a high-end live Micro-CT scanning system from Hitachi-Aloka . It is ideal for morphological observation of laboratory animals represented by mice and rats. It has nearly 200 laboratories worldwide . client. The LCT-200 provides the most advanced cadmium telluride detector for direct detection of X -ray intensity technology, providing customers with high-resolution, high-contrast, respiratory and heartbeat synchronous high-speed tomography high-quality imaging, and its powerful software database can provide 28 measurements. Indicators: including body fat percentage, subcutaneous fat content and body fat content, fatty liver analysis, brown fat analysis; bone salt density: total bone salt density, cortical bone salt density and spongy bone salt density; morphology: cortical bone thickness, Cortical bone and trabecular area ratio; minimum of mechanical properties and secondary motion of the polar area.

LCT-200 covers high-resolution imaging of living and ex vivo bones, cardiovascular research (skeletal nourishment, tissue vascularization, angiogenesis, perfusion studies, etc.), tumor models (tumor metastasis, tumor volume analysis, etc.), soft tissue enhanced visualization (organs, muscles, fat, etc.), diabetes and transgenic animal models.

First, bone research
LCT-200 can perform cortical bone area, sponge bone area, whole bone area, bone beam area, cortical bone volume, sponge bone volume, whole bone volume, bone beam volume, cortical bone density, sponge bone density, total bone density, bone Beam density, cortical bone mass, spongy bone salt, total bone salt, bone beam salt, plane bone density, bone width, cortical bone pressure, cortical bone area ratio, bone beam area ratio, minimum cross-sectional secondary moment, The measurement of 24 parameters such as the secondary moment of the section meets the various needs of bone research. The most attractive is that the LCT200 is fully capable of measuring and analyzing living bone parameters, which is a boon for many bone studies. High-quality parametric analysis can be performed without killing animals, which is of practical significance for long-term continuous observation and research of animals.
1 Analysis of rat tibia parameters

2 rat mandibular analysis

3 arthritis model analysis

It can be seen from the above experimental examples that the LCT200 can analyze various parameters of the bone without killing the animal, and has practical driving significance for bone research. Moreover, LCT200 can measure from insects, mice, rats, hamsters, guinea pigs, to bunny, so the use of animals is relatively extensive.
Second, the study of blood vessels, organs, tumors
In the presence of contrast agents, the LCT200 can perform studies of blood vessels, organs, and tumors.
1 Vascular research

2 kidney angiography

3 tumor imaging
With the LCT200 continuous angiography device, the experimental animals can be continuously injected with contrast agent, which can well complete the imaging of tumors in vivo.

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