Release date: 2008-04-10
Beauty designed a "nano machine" that kills cancer cells
American researchers have designed a "nano machine" that stores and delivers anticancer drugs and releases drugs to attack cancer cells under the influence of light. Researchers say this is the first step in using nanomachines to treat cancer.
Researchers at the University of California, Los Angeles, published a report on the online version of the new nanotechnology journal "Small," saying that the device called the "nano-propeller" is the first "nano-machine" driven by light. Can play a role in living cells. The device is made of mesoporous silicon nanoparticles, the inner pores of which are coated with the chemical azobenzene, and anticancer drugs can be loaded in such pores. Azobenzene has photochromic properties and has two modes of vibration under the action of light.
The researchers conducted experiments with a variety of human cancer cells, including colon and pancreatic cancer. They first put the above-mentioned "nano machine" into the human cancer cells placed in glassware in the dark, and then use the light to illuminate the "nano machine", and the anticancer drugs in the pores of the "nano machine" are released. Attack cancer cells. Microscopic images show that the amount of anticancer drug released can be precisely regulated by the intensity, wavelength and irradiation time of the light.
Researchers such as Professor Jeffrey Zink said that it is very exciting to develop a "nano machine" that can deal with cancer cells under the influence of light. They believe that this "nano machine" has potential applications in the precise delivery of drugs, and may become a "next-generation platform" for the treatment of cancers such as colon and stomach cancer. ——Shanghai Medical Device Industry Association
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