Merck Acquires Suvorexant Phase 3 Clinical Study for Insomnia

Merck, Inc. recently announced the successful clinical trial of Suvorexant Phase 3, an antiprogestin receptor antagonist for the treatment of insomnia.

In a multicenter, randomized, double-blind, and placebo-controlled phase 3 clinical study, a controlled study of Suvorexant and placebo was conducted in patients with insomnia aged 18 and over.

In the study of several months, four primary end points were set: the total objective sleep time, the duration of falling asleep, the duration of waking up and the potential time for starting to sleep.

Merck plans to submit a new drug listing application (NDA) to the US Food and Drug Administration (FDA) this year due to gratifying results from two Phase 3 Suvorexant clinical studies.

Peter Kim, head of Merck Research and Development Center, said: “Suvorexant can choose a path to help sleep. We are also optimistic about the drug market, and we will share the results of clinical research with relevant medical institutions.”

Flower Girl Dresses

Technical parameters:

Technical parameters

MINGTAI LED760

MINGTAI LED560

Illuminance (lux)

180,000

130,000

Color Temperature (Kelvin)

4,300

4,300

Adjustable Color Temperature (Kelvin) (Optional)

3600-5600

3600-5600

Color Rendering Index (CRI)

96

96

Red Color Index (R9)

96

96

Light brightness control

standard

standard

Brightness control range

10-100%

10-100%

Temp rise (Surgeon head) (Celsius degree)

0.5

0.5

Temp rise (surgical field) (Celsius degree)

2

2

Effective Focusing Depth (cm)

60-150

60-150

Total Irradiance Ee (W/m2)

530

470

Radiant Power Ee/ Ec (mW/m2lux)

3.3

3.3

Lighting Spot Size (mm)

100-260

100-260

Bulb Type

LED

LED

Average Bulb Life (hours)

60,000

60,000

Bulb Quantity (main bulb+ auxiliary bulb)

128LEDS+384LEDS

56LEDS+168LEDS

Depth of illumination L1+L2 (cm)

130

130

Power Consumption (W)

70

50

Height adjustment (cm)

118

118

Power Input

100-240VAC, 50/60Hz

100-240VAC, 50/60Hz

Special advantage:

Protected by patent No. ZL 2013 2 0354946.9, do not infringe

1. High strength ABS material, ultra-thin light head, integrated surrounded 4 group handle design, meeting laminar flow requirements, easy to operate

2. Intelligent spot control technology: Light intensity not change when spot size changed

3. Intelligent shadow control technology: when light was sheltered by surgeon head, correlated LED light will automatically darken, other LED lights which are not sheltered will increase brightness, compensate the illuminance loss in surgery field, provide a better shadowless rate, bring the perfect surgical lighting (optional)

4. Variety of Surgical environment lighting mode: bright, normal, endoscopic lighting mode; Base axis has ambient light lighting mode (optional)

5. Satlite oval hanging main arm, meet laminar flow requirement

6. Double control system (optional), Li battery (optional), electric focus adjustment system (optional), RGBW color adjustment system (optional), independent R9 function (optional), manual focus adjustment function (standard)

7. Base configuration: Germany imported balance arm system, light head is designed by Germany engineer, USA LED bulb, Taiwan power system

Product feature:

1. Lamp shell is ABS material, integrated design with four handles around and streamlined ultra-thin design, the thickness is not more than 18CM, obtain excellent effect of laminar flow

2. Use international advanced warm white LED as shadowless illuminant, environmental, lower energy consumption LED bulb, bulb life: 60000 hours

3. LED do not engender infrared ray and ultraviolet radiation, it doesn't have the temperature rise and tissue damage caused by halogen shadowless light, can accelerate the wound healing after surgery, and has no Radiation pollution

4. LED color temperature is constant, soft and not dazzling, close to natural light

5. The main light use 128LEDS(main bulb)+384LEDS(spare bulb) independent LED illuminant (lamp cup is one main and three spare bulb structure), divided into multiple independent illuminant group, subsidiary light use 56LEDS(main bulb)+168LEDS(spare bulb) LED illuminant (lamp cup is one main and three spare bulb structure), divided into multiple independent illuminant group; every lamp use double CPU control, every group of LED illuminant controlled by special circuit chip, any group failure will not affect the normal use of shadowless light.

6. Double switch control system, when control panel failure, emergency switch which installed on light head can be used, guarantee light normal work. Control panel in the spring arm joint, film touch switch, easy to use, Not easy to damage

7. Microcomputer digital control, illumination can be adjustable; stepless adjustment, eight segments continuous indicating, adjustment range: 10%-100%, backlight illumination: 30 Lux; it offers illuminance memory function

8. Adopt restrain interference design of electromagnetic wave, avoid disturb with the other equipment in operating room

9. Use satlite oval swing pipe design, can install 4 cantilever devices in complex operating room, also can be reserved per hospital's request, convenient to upgrade and provide perfect solution for the increasing multi-media request of hospital

10. Balanced system using imported German Ondal arm module, more than 5 group universal joints, every cantilever must has more than 3 joints which can be rotated in 360 celsius degree, equipped with fatigue correcting unit and fix position hand handle device, easy to fix position after using for long time

11. The handle on the central of lamp can be detachable, can take high temperature (134 celsius degree) sterilization treatment, easily adjust, flexible fixed; Adopt balanced arm, handy operate, and make sure the lamp stable during operation; has C-arm joint control panel, has luminance prompt facility, provide environment lighting models

12. Lamp panel radius of gyration: 182cm, the lamp can be pulled to vertical floor, convenient to any angle illumination. Unify ABS operate handle and mid-operation handle of Lamp rim convenient to operate. Product execute international IEC standard.

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Bosgoo(China)Tecgnology Co., Ltd , http://www.laohuang.com