US new technology to create a cotton candy scaffold for repairing nerve damage

Release date: 2009-04-28



Engineers at Purdue University in the United States have recently developed an innovative technology that uses cotton candy filaments to make micro-manual tube stents that can be used to repair vascular damage caused by nerve damage or disease caused by accidents. Biomedical engineer Shi Rixi and his colleagues at Purdue University published the new technology in the February 2009 issue of Langmuir.

The specific method for manufacturing the miniature artificial tube holder by this method is that the engineer first applies the degradable polymer material in the grain to the cotton candy filament, and then dissolves the cotton candy filament in the water, leaving only one root. A polymer hollow tube whose structure resembles the structure of a crisscrossed nerve. This artificial color image taken by a scanning electron microscope indicates that yellow is a cotton candy filament and blue is a polymer coating. Researchers believe their stents can act as a bridge between the injured nerve end and the tiny artificial tube. This technique can also be used to repair vascular damage caused by trauma and atherosclerosis and diseases such as diabetes. Researchers are currently focusing on applying this technique to the peripheral nerves on the limbs because nerve regeneration in the spinal cord is more complicated. Currently, there are approximately 800,000 cases of peripheral nerve injury in the United States each year, of which 50,000 require surgery. This cotton candy silk technology is expected to replace this traditional surgical treatment. This surgical treatment is to remove good nerves from the thigh or other parts of the body to repair the damaged nerves. And American researchers have developed better neurological substitutes to avoid loss of sensory function in areas where nerves are removed.

In addition, in February 2009, Cornell University researchers published a similar paper in the journal Soft Matter. They used the same technology to create a vascular network that supplies blood to tissue and transplant organs. nutrition. This artificial scaffold resembles the framework of natural nerves because the nerves are assembled from thousands of tiny tube bundles. These microtubule bundles act as outer wraps with nerve cells with conductive functions. Shanghai Medical Device Industry Association

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