First, Chinese black corn (also known as "purple jade", "black pearl") tanned black corn, plant height 110-120 cm, ear height 60-65 cm, number of main stem leaves 12-15, Number of tassels 12-15; Spring sowing period of 130 days, milk harvest 113 days of tender corn, ear conical, black grain, thin skin, ear length 13-15 cm, ear thickness 3.3-3.5 cm, There are 12-16 rows of ear rows, no baldness, about 180 grams of grain weight, and 98% double head spike rate. The blades are flushed and the plants are compact. The suitable planting density is 4500-5000 strains/mu. It can be used as fresh corn and various black corn foods. Second, the Italian black corn (also known as "Black Goddess") black tanned corn, plant height 150-160 cm, ear height 60-70 cm, the main stem leaves number 12-15, the number of tassels branch 15 -17 tablets, 143 days of spring sowing period, 115 days of harvesting of tender corn at milk ripening period, rushing on leaves, conical heads, black seeds, thin skin, ear length 13-15 cm, ear rows 12-16 rows, ear About 3.5 centimeters thick, 1000 grams weight 190 grams, double spike rate of 100%, plant compact, suitable for planting density of 4545-5000 / acre, can be used as fresh corn processing black corn food selection. Third, "Black Sweet 16" black corn (also known as "black rose") sweet type, plant height 160-170 cm, ear height 50-60 cm, the main stem leaves number 15, tassel number of branches 12 -15 tablets, spring sowing period 110 days, milk ripening and harvesting tender corn for 90 days, ear drum type, ear rows 14-16 rows, spike length 16-18 cm, ear thickness 4.0-4.3 cm, The double ear rate is 40%, and the suitable planting density is 3500-4000 plants/mu, which can be used as raw black corn processing. IV. "Taihei No. 1" black corn (also known as "black one") hard blackish corn, plant height 200-220 cm, ear height 95-100 cm, number of main stem leaves 11--13 , Number of tassels 25-30 tablets, spring sowing 105 days, ear drum type, ear length 24-26 cm, ear thickness 3.5-4.0 cm, ear rows 10-12 lines, 1000 grain weight 255 Grams, double ear rate 10%, suitable for planting density 3500-4000 strains / acre, can be used for processing a variety of black corn food selection. V. "Taihei 2" black corn (also known as "black peony") hard black corn, plant height 220-230 cm, ear height 100-105 cm, spring sowing period 110 days, number of main stem leaves 13 tablets, 20 tassel branches, ear-drum type, ear length 22-24 cm, ear thickness 4-4.5 cm, ear rows 14-16 rows, 1000-grain weight 320 g, double ear rate 15%, The suitable planting density is 3500-4000 plants/mu. , can be used for processing a variety of black corn food selection. 6. "Taihe No. 3" black corn (also known as "black girl") is of tan type, black grain, thin skin, 160-170 cm in plant height, 65-70 cm in ear height, and 18 leaves of main stem The number of tassels was 25, and the spring sowing period was 130 days. The tender corn was harvested for 110 days. The leaves were flushed. The plant type was compact, the ear was conical, the ear length was 15-18 cm, and the ear was about 4.0 cm thick. , 210-grain weight 210 grams, no baldness, double spike rate of 100%, suitable for fresh food, processing frozen corn and a variety of black corn food, suitable for planting density of 400-4500 strains / acre.
Ibrutinib is a small molecule drug that binds permanently to a protein, Bruton's tyrosine kinase (BTK) that is important in B cells; the drug is used to treat B cell cancers like mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenstrom's macroglobulinemia, a form of non-Hodgkin's lymphoma.
Ibrutinib is used to treat chronic lymphocytic leukemia, Waldenstrom's macroglobulinemia, and as a second-line treatment for mantle cell lymphoma, and marginal zone lymphoma.
We produce a series of complete intermediates for Ibrutinib, intermediate I (CAS No. 330786-24-8) and intermediate II (CAS No. 143900-44-1) etc.
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Ibrutinib Intermediates
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