Hovenia Dulcis Extract Dihydromyricetin (DHM) 1%-20%

What is Hovenia dulcis Extract?
 Hovenia dulcis, the oriental raisin tree, is a hardy tree found from Asia, over Eastern China  and Korea to the Himalayas(up to altitudes of 2,000 m), growing preferably in a sunny position on moist sandy or loamy soils. The tree has been introduced as an ornamental tree to several countries, and the fruit is also edible.

Uses
The fleshy rachis of the infructescence is sweet, fragrant and is edible raw or cooked. Dried, they look and taste like raisins. An extract of the seeds, bough and young leaves can be used as a substitute for honey and is used for making wine and candy.
An extract of the leave contains hodulcine, a glycoside which exhibits an anti-sweet activity.Ampelopsin is a flavanonol found in H. dulcis and is credited with hepatoprotective effects.
The timber is fine and hard and is used for building construction and fine furniture.
Health products
The Korea Food & Drug Administration approved in December 2008 that extracts of the Hovenia dulcis fruit can protect and help recover the liver from substances such as alcohol. The main chemical for this effect in Hovenia dulcis is Quercetin, which has anti-inflammatory and anti-oxidant properties.
There is a commercially available dairy product in Korea called Kupffers offers 2,460 mg of Hovenia dulcis extract.
Dihydromyricetin can be isolated from Hovenia dulcis and is under study as an alcohol antagonist and as a treatment for alcoholism.
Liver Health of Hovenia dulcis Extract
Hovenia dulcis (Japanese Raisin Tree) is a source of dihydromyricetin (Ampelopsin) and has traditionally been used as an anti-Alcohol herb and hangover cure. At least one human study has noted that, when taken before drinking, it can reduce circulating levels of alcohol.

Ampelopsin is a potent inhibitor of VEGF and bFGF expression and production in human hepatocellular carcinoma Bel-7402 cell, and may be a promising angiogenesis inhibitor.
This study found an inhibitory effect of ampelopsin on the growth of human hepatocellular carcinoma Bel-7402, which suggests it may help to prevent malignant hepatocellular carcinoma, the most common form of liver cancer.
Anti-diabetic and Hovenia dulcis Extract
 Hovenia dulcis Thunb, a food supplement and traditional medicine used in East Asia, has been demonstrated to exhibit hepatoprotective, antimicrobial, neuroprotective, and anti-oxidant activities. To evaluate the anti-oxidant activities of H.dulcis in STZ-induced diabetic mice, the different extracting solvents were employed to compare the antioxidant activity by the classical Fenton's reagent, the concentrations of SOD, MDA, and iNOS in the serum were determined. The results showed that the ethanol (70%) exhibited the most effective antioxidant activity and dose-dependently upregulation of SOD and downregulation of MDA and iNOS significantly in STZ-induced diabetic mice. These indicated that H.dulcis displayed remarkable anti-diabetic activity.

FAQ
Q1How is your quality of raw materials guaranteed?
A1: We select the best raw materials in the first step for further processing. The facility is GMP compliant, and no contamination is possible. All testing equipment are brand new and advanced. Some of our products also have third-party lab certificates. Certificate of analysis is obtainable for all ingredients from New Natural biotechnology.

Q2: What's your MOQ( Minimum Order Quantity )?
A2: Our MOQ is usually 25kg since our package is 25kg/drum. For high-value products, 1kg/bag is available. Of course, we are also to pack according to your demand. If quantity smaller than MOQ, the unit price may be a little higher, hope you may understand. Larger quantity enjoys much better pricing.

Q3: How long May I receive the items after payment?
A3: It usually takes 3-5 working days after receiving the payment, and shipping time for express is about 2-3 days depends to your destination. Therefore, it takes about 7 days all together. If no stock, make take another week.

  What is Hovenia dulcis Extract?
 Hovenia dulcis, the oriental raisin tree, is a hardy tree found from Asia, over Eastern China  and Korea to the Himalayas(up to altitudes of 2,000 m), growing preferably in a sunny position on moist sandy or loamy soils. The tree has been introduced as an ornamental tree to several countries, and the fruit is also edible.

Uses
The fleshy rachis of the infructescence is sweet, fragrant and is edible raw or cooked. Dried, they look and taste like raisins. An extract of the seeds, bough and young leaves can be used as a substitute for honey and is used for making wine and candy.
An extract of the leave contains hodulcine, a glycoside which exhibits an anti-sweet activity.Ampelopsin is a flavanonol found in H. dulcis and is credited with hepatoprotective effects.
The timber is fine and hard and is used for building construction and fine furniture.
Health products
The Korea Food & Drug Administration approved in December 2008 that extracts of the Hovenia dulcis fruit can protect and help recover the liver from substances such as alcohol. The main chemical for this effect in Hovenia dulcis is Quercetin, which has anti-inflammatory and anti-oxidant properties.
There is a commercially available dairy product in Korea called Kupffers offers 2,460 mg of Hovenia dulcis extract.
Dihydromyricetin can be isolated from Hovenia dulcis and is under study as an alcohol antagonist and as a treatment for alcoholism.
Liver Health of Hovenia dulcis Extract
Hovenia dulcis (Japanese Raisin Tree) is a source of dihydromyricetin (Ampelopsin) and has traditionally been used as an anti-Alcohol herb and hangover cure. At least one human study has noted that, when taken before drinking, it can reduce circulating levels of alcohol.

Ampelopsin is a potent inhibitor of VEGF and bFGF expression and production in human hepatocellular carcinoma Bel-7402 cell, and may be a promising angiogenesis inhibitor.
This study found an inhibitory effect of ampelopsin on the growth of human hepatocellular carcinoma Bel-7402, which suggests it may help to prevent malignant hepatocellular carcinoma, the most common form of liver cancer.
Anti-diabetic and Hovenia dulcis Extract
 Hovenia dulcis Thunb, a food supplement and traditional medicine used in East Asia, has been demonstrated to exhibit hepatoprotective, antimicrobial, neuroprotective, and anti-oxidant activities. To evaluate the anti-oxidant activities of H.dulcis in STZ-induced diabetic mice, the different extracting solvents were employed to compare the antioxidant activity by the classical Fenton's reagent, the concentrations of SOD, MDA, and iNOS in the serum were determined. The results showed that the ethanol (70%) exhibited the most effective antioxidant activity and dose-dependently upregulation of SOD and downregulation of MDA and iNOS significantly in STZ-induced diabetic mice. These indicated that H.dulcis displayed remarkable anti-diabetic activity.

FAQ
Q1How is your quality of raw materials guaranteed?
A1: We select the best raw materials in the first step for further processing. The facility is GMP compliant, and no contamination is possible. All testing equipment are brand new and advanced. Some of our products also have third-party lab certificates. Certificate of analysis is obtainable for all ingredients from New Natural biotechnology.

Q2: What's your MOQ( Minimum Order Quantity )?
A2: Our MOQ is usually 25kg since our package is 25kg/drum. For high-value products, 1kg/bag is available. Of course, we are also to pack according to your demand. If quantity smaller than MOQ, the unit price may be a little higher, hope you may understand. Larger quantity enjoys much better pricing.

Q3: How long May I receive the items after payment?
A3: It usually takes 3-5 working days after receiving the payment, and shipping time for express is about 2-3 days depends to your destination. Therefore, it takes about 7 days all together. If no stock, make take another week.